BDBM50055366 (3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-acetic acid::(3-Aminooxalyl-1-benzyl-2-ethyl-2,3-dihydro-1H-indol-4-yloxy)-acetic acid::2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid::CHEMBL148674::Varespladib sodium

SMILES CCc1c(C(=O)C(N)=O)c2c(OCC(O)=O)cccc2n1Cc1ccccc1

InChI Key InChIKey=BHLXTPHDSZUFHR-UHFFFAOYSA-N

Data  60 IC50

PDB links: 3 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50055366   

TargetPhospholipase A2 group V(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human recombinant sPLA2 G5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  750nMAssay Description:Inhibition of mouse recombinant sPLA2 G5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  500nMAssay Description:Inhibition of human group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Mus musculus)
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  750nMAssay Description:Inhibition of mouse group2V phospholipase A2 fluorimetric assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPhospholipase A2 group V(Homo sapiens (Human))
University Of Washington

Curated by ChEMBL
LigandPNGBDBM50055366((3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-...)
Affinity DataIC50:  124nMAssay Description:Inhibition of recombinant human sPLA2-5 expressed in Escherichia coli BL21(DE3) using 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine as substrate p...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed